The answer to this is complex based on how we define “curse” and who we mean when we say “us.” Here is a quick attempt at an answer. There are three ways to think about this:
1. All Humanity Is Currently Under A Curse from God
The curse from Genesis 3 has not been lifted yet. God has cursed the ground, work, parenting, and our bodies with disease and death. These curses still stand. In fact a curse from God still resides on all creation: “For the creation was subjected to futility, not willingly, but because of him who subjected it, in hope that the creation itself will be set free from its bondage to corruption and obtain the freedom of the glory of the children of God” (Romans 8:20-21) So, we are all under a curse in a sense, so that we don’t hold on to this world but rather are motivated to cling to God. Work is hard. The weather is bad. Parenting is hard. The threat of physical and spiritual death loom on the horizon. These are real curses from God, as a result of sin, to turn us away from sin.
2. God is Always Actively Opposed to the Wicked (all of us before knowing Christ)
God is actively opposed to evil doers (Proverbs 6:16, Hosea 9:15; Psalm 5:5; Psalm 11:5; Psalm 139:22) God’s Word says three times in Romans 1 that for those who persist in sin, which again is all of us before turning to Christ, that He “gave them up” to do evil (Romans 1:24, 26, 28). Those who have not believed in Christ are “condemned already” (John 3:18). At least twice we read about such things as “a harmful spirit from the Lord” who tormented Saul (1 Sam 16:14, 18:10). God is in charge of the universe, including evil spirits. So if there is any evil that occurs, it is only because God has allowed it to happen, and God does everything with precision and purpose. Since God is opposed to evil, there is a special way in which God is actively opposing those set on evil, which is everyone single one of us, before we turn to Christ.
3. God is Only Ever Blessing Believers
Believers are those who trust that, without ceasing to be God, God became the man Jesus Christ; that He died to pay a debt we couldn’t pay, and rose from the dead so that all who turn from sin and trust in Him alone (not hoping in our own goodness) will also live forever with Him. While believers today still deal with results of the curse from God in Genesis 3 (our work is hard, the planet is harsh, parenting is hard, we get sick, we die, etc) — there is “no condemnation for those in Christ Jesus.” (Romans 8:1) The final effects of these curses have been lifted, namely eternal death (and possibly physical death if Christ returns today). We are free from the “curse” of the law today. (Galatians 3:13) We’re promised eternal life and freedom from the curse of death and every other temporary curse on this world. Additionally, for the believer, God works all things for our good (Romans 8:28). So aside from the curse on our planet, God is never cursing believers, He is only ever blessing them. He may train and discipline us, and that may seem painful at first, but it produces a crop of righteousness. (Hebrews 12:11) But he does not ever punish us because Christ has already taken every punishment for every sin. God is never angry at believers. For believers, all of his wrath has been satisfied in Jesus. This is what the word propitiation means in 1 John 2:2 –a turning away of the anger or wrath of God. We now have in us Christ’s own righteousness (2 Cor 5:21) and we wear it like armor (Ephesians 6). How incredibly good and gracious God has been to save us from sin and death and assure us of His eternal love!